About Us
Built by data scientists who got tired of doing it the hard way.
NotchBio was born in RNA sequencing labs across the United States, founded by two data scientists who spent years automating bulk RNA-seq analysis and decided every lab should have access to the same tooling.
Our story
We've been on both sides of the bench, writing R scripts at 2 AM to rerun a DESeq2 analysis with different parameters, debugging Salmon index builds that silently failed, waiting days for shared HPC cluster time just to trim reads with fastp.
The tools themselves are excellent. The problem is the glue: provisioning compute, managing file transfers, tracking which parameter set produced which result, and remembering how to wire one tool's output into the next tool's input. That's the work nobody trains you for, and it's where most time gets lost.
NotchBio wraps the full bulk RNA-seq pipeline (quality control, preprocessing, quantification, differential expression, and pathway analysis) into a single managed platform. Every run is versioned, every parameter set is tracked, and results are available as interactive visualizations and downloadable files ready for publication.
We built it because we needed it. Now we want every lab to have it.
What drives us
Built by researchers, for researchers
We spent years running RNA-seq pipelines manually, writing custom scripts, waiting on shared clusters, and debugging failed jobs at midnight. NotchBio is the platform we wished existed.
Reproducibility first
Every pipeline run is versioned with its exact parameters. Compare results across parameter variations and know exactly how each output was produced.
No infrastructure burden
We handle compute provisioning, scaling, and storage so you can focus on the biology. Upload your files, configure your analysis, and get results without worrying about server errors.
Ready to simplify your RNA-seq workflow?
Start with a free workspace. No credit card required.