Welcome to the NotchBio Blog
We’re excited to launch the NotchBio blog! This is where we’ll share insights on RNA-seq analysis, bioinformatics best practices, platform updates, and tutorials to help you get the most out of your research data.
What to Expect
Our blog will cover a range of topics designed to help both new and experienced researchers:
- Platform updates — New features, improvements, and what’s coming next
- RNA-seq tutorials — Step-by-step guides for common analysis workflows
- Bioinformatics insights — Tips, best practices, and deep dives into methods
- Research highlights — How teams are using NotchBio in their work
Our Mission
NotchBio was built to make bulk RNA-seq analysis accessible, reproducible, and fast. We believe researchers should spend their time on science — not wrestling with command-line tools, dependency issues, or infrastructure management.
What Makes NotchBio Different
Our platform handles the entire RNA-seq pipeline in the cloud:
- Quality Control — Automated QC reports for your raw FASTQ files
- Preprocessing — fastp-powered trimming with configurable parameters
- Quantification — Salmon for fast, accurate transcript quantification
- Differential Expression — DESeq2 with interactive volcano plots and heatmaps
- Gene Set Enrichment — GSEA to identify enriched biological pathways
Everything is versioned, reproducible, and shareable with your team.
Coming Up Next
In the coming weeks, we’ll be publishing:
- A complete guide to understanding your fastp QC reports
- Best practices for experimental design in RNA-seq
- How to interpret DESeq2 volcano plots and MA plots
- Tips for setting up your first NotchBio project
We’re looking forward to building this resource with you. If there’s a topic you’d like us to cover, don’t hesitate to reach out.
Happy analyzing! — The NotchBio Team